Rational proteomics V: Structure-based mutagenesis has revealed key residues responsible for substrate recognition and catalysis by the dehydrogenase and isomerase activities in human 3beta-hydroxysteroid dehydrogenase/isomerase type 1.

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Rational proteomics V: Structure-based mutagenesis has revealed key residues responsible for substrate recognition and catalysis by the dehydrogenase and isomerase activities in human 3beta-hydroxysteroid dehydrogenase/isomerase type 1.

Pletnev VZ, Thomas JL, Rhaney FL, Holt LS, Scaccia LA, Umland TC, Duax WL.

Hauptman-Woodward Medical Research Institute & Department of Structural Biology, SUNY at Buffalo, 700 Ellicott St., Buffalo, NY 14203, USA; Institute of Bioorganic Chemistry RAS, Ul. Miklukho-Maklaya, 16/10, 117997 Moscow, Russia.

Publication Date: Monday, August 07, 2006

Click here to view MEDLINE citation

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