Pharmacogenetics of headache treatment.
by Montagna P, Pierangeli G, Cevoli S, Mochi M, Cortelli P.
Affliation: Department of Clinical Neurology, University of Bologna Medical School, Via Ugo Foscolo 7, I-40123, Bologna, Italy. pmontagn@neuro.unibo.it
Journal: Neurol Sci. 26 Suppl 2:s143-7
Publication Date: Tuesday, May 31, 2005
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Drug metabolism and variability among patients in drug response.
by Wilkinson GR.
Affliation: Department of Pharmacology, Vanderbilt University, Nashville, TN 37232-6600, USA. grant.wilkinson@vanderbilt.edu
Journal: N Engl J Med. 352(21):2211-21
Publication Date: Thursday, May 26, 2005
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Measuring the value of pharmacogenomics.
by Phillips KA, Van Bebber SL.
Affliation: School of Pharmacy and Institute for Health Policy Studies, University of California, San Francisco, 3333 California Street, Box 0613, San Francisco, California 94143, USA.
Journal: Nat Rev Drug Discov. :
Publication Date: Wednesday, May 25, 2005
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How the Monoamine Transporter Garden Grows (Relates to Article by Hahn, et al. FastForward 13 May 2005).
by Ruoho AE.
Affliation: University of Wisconsin Medical School.
Journal: Mol Pharmacol. :
Publication Date: Tuesday, May 24, 2005
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Pharmacological properties of the Cys23Ser single nucleotide polymorphism in human 5-HT(2C) receptor isoforms.
by Fentress HM, Grinde E, Mazurkiewicz JE, Backstrom JR, Herrick-Davis K, Sanders-Bush E.
Affliation: 1Department of Pharmacology and Neuroscience Graduate Program, Vanderbilt University School of Medicine, Nashville, TN, USA.
Journal: Pharmacogenomics J. :
Publication Date: Tuesday, May 24, 2005
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A Single Administration of Recombinant Human Interleukin-12 Is Associated With Increased Expression Levels of Interferon-gamma and Signal Transducer and Activator of Transcription in Healthy Subjects.
by Trudeau C, Cotreau MM, Stonis L, Dykstra KH, Oestreicher JL, Strahs A, Dorner AJ, Van Cleave VH, Trepicchio WL, Schwertschlag US.
Affliation: Wyeth Research, 35 Cambridge Park Drive, Cambridge, MA 02140.
Journal: J Clin Pharmacol. 45(6):649-58
Publication Date: Thursday, May 19, 2005
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Methotrexate-induced pancytopenia: serious and under-reported? Our experience of 25 cases in 5 years.
by Lim AY, Gaffney K, Scott DG.
Affliation: Rheumatology Department, Norfolk and Norwich University Hospital, Norwich NR4 7UY, UK.
Journal: Rheumatology (Oxford). :
Publication Date: Thursday, May 19, 2005
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FDA pharmacogenomics guidance sends clear message to industry.
by Ratner M.
Affliation:
Journal: Nat Rev Drug Discov. 4(5):359
Publication Date: Thursday, May 19, 2005
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Cytochrome P450 2C8: substrates, inhibitors, pharmacogenetics, and clinical relevance.
by Totah RA, Rettie AE.
Affliation: Department of Medicinal Chemistry, University of Washington, Seattle, WA 98195, USA.
Journal: Clin Pharmacol Ther. 77(5):341-52
Publication Date: Wednesday, May 18, 2005
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Genotype-phenotype associations of cytochrome P450 3A4 and 3A5 polymorphism with midazolam clearance in vivo.
by He P, Court MH, Greenblatt DJ, Von Moltke LL.
Affliation: Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, 136 Harrison Ave, Boston, MA 02111, USA.
Journal: Clin Pharmacol Ther. 77(5):373-87
Publication Date: Wednesday, May 18, 2005
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Human response to alpha2-adrenergic agonist stimulation studied in an isolated vascular bed in vivo: Biphasic influence of dose, age, gender, and receptor genotype.
by King D, Etzel JP, Chopra S, Smith J, Cadman PE, Rao F, Funk SD, Rana BK, Schork NJ, Insel PA, O'Connor DT.
Affliation: Department of Medicine and Center for Molecular Genetics (0838), University of California at San Diego, and VA San Diego Healthcare System, 9500 Gilman Dr, La Jolla, CA 92093-0838, USA.
Journal: Clin Pharmacol Ther. 77(5):388-403
Publication Date: Wednesday, May 18, 2005
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Role of CYP2C9 and its variants (CYP2C9*3 and CYP2C9*13) in the metabolism of lornoxicam in humans.
by Guo Y, Zhang Y, Wang Y, Chen X, Si D, Zhong D, Fawcett JP, Zhou H.
Affliation: College of Life Science, Jilin University, No.115 Jiefang Road, Changchun, 130023, China.
Journal: Drug Metab Dispos. 33(6):749-53
Publication Date: Tuesday, May 17, 2005
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A common PCSK9 haplotype, encompassing the E670G coding single nucleotide polymorphism, is a novel genetic marker for plasma low-density lipoprotein cholesterol levels and severity of coronary atherosclerosis.
by Chen SN, Ballantyne CM, Gotto AM, Tan Y, Willerson JT, Marian AJ.
Affliation: Section of Cardiology, Center for Preventive Cardiology, Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA.
Journal: J Am Coll Cardiol. 45(10):1611-9
Publication Date: Monday, May 16, 2005
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Metabolic profile of XK469 (2(R)-[4-(7-chloro-2-quinoxalinyl)oxyphenoxy]-propionic acid; NSC698215) in patients and in vitro: low potential for active or toxic metabolites or for drug-drug interactions.
by Anderson LW, Collins JM, Klecker RW, Katki AG, Parchment RE, Boinpally RR, Lorusso PM, Ivy SP.
Affliation: Food and Drug Administration, WO Bldg 64, Rm 2014, 10903 New Hampshire Avenue, HFD-902, Silver Spring, MD, 20993.
Journal: Cancer Chemother Pharmacol. :
Publication Date: Monday, May 16, 2005
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Pharmacogenetics for individualized cancer chemotherapy.
by Efferth T, Volm M.
Affliation: German Cancer Research Center, M070, Im Neuenheimer Feld 282, 69120 Heidelberg, Germany.
Journal: Pharmacol Ther. :
Publication Date: Friday, May 13, 2005
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Gene variants explain patient differences in antiepileptic drug responses.
by Hampton T.
Affliation:
Journal: JAMA. 293(18):2199
Publication Date: Wednesday, May 11, 2005
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Pharmacogenetics and rheumatology: Molecular mechanisms contributing to variability in drug response.
by Asanuma Y, Xie HG, Stein CM.
Affliation: Vanderbilt University School of Medicine, Nashville, Tennessee.
Journal: Arthritis Rheum. 52(5):1349-1359
Publication Date: Wednesday, May 11, 2005
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Insights into TOR function and rapamycin response: Chemical genomic profiling by using a high-density cell array method.
by Xie MW, Jin F, Hwang H, Hwang S, Anand V, Duncan MC, Huang J.
Affliation: Departments of Molecular and Medical Pharmacology and Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, CA 90095.
Journal: Proc Natl Acad Sci U S A. :
Publication Date: Tuesday, May 10, 2005
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Common VKORC1 and GGCX polymorphisms associated with warfarin dose.
by Wadelius M, Chen LY, Downes K, Ghori J, Hunt S, Eriksson N, Wallerman O, Melhus H, Wadelius C, Bentley D, Deloukas P.
Affliation: 1Department of Medical Sciences, Clinical Pharmacology, University Hospital, Uppsala, Sweden.
Journal: Pharmacogenomics J. :
Publication Date: Tuesday, May 10, 2005
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Pharmacogenetics and ethnically targeted therapies.
by Rahemtulla T, Bhopal R.
Affliation:
Journal: BMJ. 330(7499):1036-7
Publication Date: Monday, May 09, 2005
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